GNAS1

GNAS

Protein GNAS PDB 1azs.png

Identifiers

GNAS, AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, POH, SCG6, SgVI, GNAS complex locus

External IDs

OMIM: 139320 MGI: 95777 HomoloGene: 55534 GeneCards: GNAS

Gene ontology
Molecular function	• molecular function • nucleotide binding • G-protein beta/gamma-subunit complex binding • GTP binding • signal transducer activity • metal ion binding • protein binding • GTPase activity • guanyl nucleotide binding • insulin-like growth factor receptor binding • mu-type opioid receptor binding • corticotropin-releasing hormone receptor 1 binding • beta-2 adrenergic receptor binding • ionotropic glutamate receptor binding • D1 dopamine receptor binding
Cellular component	• cytoplasm • perinuclear region of cytoplasm • extracellular region • transport vesicle • cytoplasmic vesicle • nucleus • cytosol • trans-Golgi network membrane • membrane • plasma membrane • heterotrimeric G-protein complex • intrinsic component of membrane • extracellular exosome • ruffle • cell projection • dendrite • apical plasma membrane
Biological process	• female pregnancy • negative regulation of multicellular organism growth • response to parathyroid hormone • protein secretion • hair follicle placode formation • positive regulation of cAMP biosynthetic process • cellular response to catecholamine stimulus • G-protein coupled receptor signaling pathway • adenylate cyclase-activating dopamine receptor signaling pathway • adenylate cyclase-activating G-protein coupled receptor signaling pathway • cognition • regulation of insulin secretion • cellular response to glucagon stimulus • intracellular transport • positive regulation of cAMP-mediated signaling • activation of adenylate cyclase activity • cellular response to prostaglandin E stimulus • adenylate cyclase-activating adrenergic receptor signaling pathway • sensory perception of smell • positive regulation of GTPase activity • developmental growth • renal water homeostasis • bone development • platelet aggregation • signal transduction • regulation of signal transduction • skeletal system development • genetic imprinting • multicellular organism growth • positive regulation of osteoclast differentiation • endochondral ossification • regulation of parathyroid hormone secretion • post-embryonic development • post-embryonic body morphogenesis • DNA methylation • cartilage development • positive regulation of osteoblast differentiation • tissue homeostasis • sensory perception of chemical stimulus • embryonic cranial skeleton morphogenesis • energy reserve metabolic process • response to drug • skin development • embryonic hindlimb morphogenesis
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE GNAS 200780 x at fs.png

PBB GE GNAS 200981 x at fs.png

PBB GE GNAS 211858 x at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


2778


14683


ENSG00000087460


ENSMUSG00000027523


O95467 P63092 P84996 Q5JWF2


P63094 Q6R0H7 Q9Z0F1 Q6R0H6

RefSeq (mRNA)

NM_000516 NM_001077488 NM_001077489 NM_001077490 NM_001309840
NM_001309842 NM_001309861 NM_001309883 NM_016592 NM_080425 NM_080426

NM_001077507 NM_001077510 NM_010309 NM_010310 NM_019690
NM_022000 NM_201616 NM_201617 NM_201618 NM_001310083 NM_001310085

RefSeq (protein)

NP_000507.1 NP_001070956.1 NP_001070957.1 NP_001296790.1 NP_057676.1
NP_536351.1 NP_000507.1 NP_001070956.1 NP_001070957.1 NP_001070958.1 NP_001296769.1 NP_536350.2 NP_536351.1 NP_001070958.1 NP_001296812.1 NP_001296812.1 NP_536350.2

NP_001070978.1 NP_001297012.1 NP_963910.1 NP_001070975.1 NP_001297014.1
NP_034439.2 NP_963911.1 NP_062664.2 NP_068840.2 NP_001070975.1 NP_001297014.1 NP_963911.1 NP_963912.1

Location (UCSC)

Chr 20: 58.84 – 58.91 Mb

Chr 2: 174.28 – 174.35 Mb

PubMed search

ENSG00000087460

ENSMUSG00000027523

O95467
P63092
P84996
Q5JWF2

P63094
Q6R0H7
Q9Z0F1
Q6R0H6

NM_001309842
NM_001309861
NM_001309883
NM_016592
NM_080425
NM_080426

NM_022000
NM_201616
NM_201617
NM_201618
NM_001310083
NM_001310085

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Wikipedia

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