GLUD2

GLUD2
Identifiers
Aliases	GLUD2, GDH2, GLUDP1, glutamate dehydrogenase 2
External IDs	HomoloGene: 115647 GeneCards: GLUD2
Gene location (Human) Chr. X chromosome (human) Band Xq24 Start 121,047,588 bp End 121,050,080 bp
Gene ontology Molecular function • ADP binding • oxidoreductase activity • GTP binding • leucine binding • glutamate dehydrogenase [NAD(P)+ activity] • glutamate dehydrogenase (NAD+) activity • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor Cellular component • cytoplasm • mitochondrion Biological process • cellular amino acid metabolic process • glutamate metabolic process • glutamate catabolic process • glutamate biosynthetic process • oxidation-reduction process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	2747	n/a
Ensembl	ENSG00000182890	n/a
UniProt	P49448	n/a
RefSeq (mRNA)	NM_012084	n/a
RefSeq (protein)	NP_036216	n/a
Location (UCSC)	Chr X: 121.05 – 121.05 Mb	n/a
PubMed search		n/a

2747

n/a

ENSG00000182890

n/a

P49448

n/a

NM_012084

n/a

NP_036216

n/a

Glutamate dehydrogenase 2, mitochondrial, also known as GDH 2, is an enzyme that in humans is encoded by the GLUD2 gene. This dehydrogenase is one of the family of glutamate dehydrogenases that are ubiquitous in life.

Glutamate dehydrogenase 2 is localized to the and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate.

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Wikipedia