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GHIH

SST
Somatostatin.svg
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SST, SMST, somatostatin, Somatostatin
External IDs OMIM: 182450 MGI: 98326 HomoloGene: 819 GeneCards: SST
RNA expression pattern
PBB GE SST 213921 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001048

NM_009215

RefSeq (protein)

NP_001039

NP_033241.1
NP_033241

Location (UCSC) Chr 3: 187.67 – 187.67 Mb Chr 16: 23.89 – 23.89 Mb
PubMed search

2MI1

NM_001048

NM_009215

NP_001039

NP_033241.1
NP_033241

Somatostatin, also known as growth hormone–inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin inhibits insulin and glucagon secretion.

Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids (shown in infobox to right), the other of 28 amino acids which is the short form with another 14 amino acids at one end.


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Wikipedia

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