GFRα3

GFRA3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2GH0
Identifiers
Aliases	GFRA3, GDNFR3, GDNF family receptor alpha 3
External IDs	MGI: 1201403 HomoloGene: 1146 GeneCards: GFRA3
Genetically Related Diseases
smallpox
Gene ontology Molecular function • receptor activity • receptor binding • axon guidance receptor activity • Ras guanyl-nucleotide exchange factor activity Cellular component • membrane • anchored component of membrane • external side of plasma membrane • extrinsic component of membrane • plasma membrane • cytosol Biological process • neuron development • neuron migration • peripheral nervous system development • sympathetic nervous system development • signal transduction • nervous system development • MAPK cascade • positive regulation of GTPase activity • axon guidance Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2676	14587
Ensembl	ENSG00000146013	ENSMUSG00000024366
UniProt	O60609	O35118
RefSeq (mRNA)	NM_001496	NM_010280
RefSeq (protein)	NP_001487	NP_034410.3 NP_034410
Location (UCSC)	Chr 5: 138.25 – 138.27 Mb	Chr 18: 34.69 – 34.72 Mb
PubMed search

2GH0

2676

14587

ENSG00000146013

ENSMUSG00000024366

O60609

O35118

NM_001496

NM_010280

NP_001487

NP_034410.3
NP_034410

GDNF family receptor alpha-3 (GFRα3), also known as the artemin receptor, is a protein that in humans is encoded by the GFRA3 gene.

The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.

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Wikipedia