GAT-1

SLC6A1
Identifiers
Aliases	SLC6A1, GABATHG, GABATR, GAT1, MAE, GABA transporter 1, solute carrier family 6 member 1
External IDs	MGI: 95627 HomoloGene: 2290 GeneCards: SLC6A1
Gene location (Human) Chr. Chromosome 3 (human) Band 3p25.3 Start 10,992,724 bp End 11,039,247 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6|6 E3 Start 114,282,635 bp End 114,317,532 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • metal ion binding • neurotransmitter:sodium symporter activity • symporter activity • gamma-aminobutyric acid:sodium symporter activity Cellular component • integral component of membrane • membrane • plasma membrane • integral component of plasma membrane • cell surface • axon • neuron projection Biological process • chemical synaptic transmission • response to estradiol • response to organic cyclic compound • learning • response to organic substance • response to purine-containing compound • response to calcium ion • gamma-aminobutyric acid transport • gamma-aminobutyric acid import • negative regulation of synaptic transmission, GABAergic • response to lead ion • response to organonitrogen compound • positive regulation of gamma-aminobutyric acid secretion • protein homooligomerization • response to toxic substance • response to sucrose • response to cocaine • transmembrane transport • neurotransmitter transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6529	232333
Ensembl	ENSG00000157103	ENSMUSG00000030310
UniProt	P30531	P31648
RefSeq (mRNA)	NM_003042 NM_001348250 NM_001348251 NM_001348252 NM_001348253	NM_178703
RefSeq (protein)	NP_003033 NP_001335179 NP_001335180 NP_001335181 NP_001335182	NP_848818
Location (UCSC)	Chr 3: 10.99 – 11.04 Mb	Chr 3: 114.28 – 114.32 Mb
PubMed search

6529

232333

ENSG00000157103

ENSMUSG00000030310

P30531

P31648

NM_003042
NM_001348250
NM_001348251
NM_001348252
NM_001348253

NM_178703

NP_003033
NP_001335179
NP_001335180
NP_001335181
NP_001335182

NP_848818

GABA transporter 1 (GAT1) also known as sodium- and chloride-dependent GABA transporter 1 is a protein that in humans is encoded by the SLC6A1 gene.

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Wikipedia