GABARAP

GABARAP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1GNU, 1KLV, 1KM7, 1KOT, 3D32, 3DOW, 3WIM, 4XC2
Identifiers
Aliases	GABARAP, ATG8A, GABARAP-a, MM46, GABA type A receptor-associated protein
External IDs	MGI: 1861742 HomoloGene: 134119 GeneCards: GABARAP
Gene ontology Molecular function • GABA receptor binding • microtubule binding • protein binding • beta-tubulin binding • ubiquitin protein ligase binding Cellular component • cytoplasm • cell body • Golgi apparatus • membrane • Golgi membrane • plasma membrane • microtubule associated complex • smooth endoplasmic reticulum • autophagosome • autophagosome membrane • actin cytoskeleton • perinuclear region of cytoplasm • axoneme • lysosome • sperm midpiece • cytoskeleton • microtubule • cytoplasmic vesicle • endomembrane system • cytosol Biological process • chemical synaptic transmission • protein targeting • autophagy • protein transport • macroautophagy • microtubule cytoskeleton organization • extrinsic apoptotic signaling pathway via death domain receptors • apoptotic process • membrane organization • autophagosome maturation • autophagosome assembly • mitophagy • cellular response to nitrogen starvation • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	11337	56486
Ensembl	ENSG00000170296	ENSMUSG00000018567
UniProt	O95166	Q9DCD6
RefSeq (mRNA)	NM_007278	NM_019749
RefSeq (protein)	NP_009209	NP_062723
Location (UCSC)	Chr 17: 7.24 – 7.24 Mb	Chr 11: 69.99 – 69.99 Mb
PubMed search

1GNU, 1KLV, 1KM7, 1KOT, 3D32, 3DOW, 3WIM, 4XC2

11337

56486

ENSG00000170296

ENSMUSG00000018567

O95166

Q9DCD6

NM_007278

NM_019749

NP_009209

NP_062723

Gamma-aminobutyric acid receptor-associated protein is a protein that in humans is encoded by the GABARAP gene.

Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.

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Wikipedia