Furnace Creek is a stream in Washington County in the U.S. state of Missouri. It is a tributary of the Big River.
The stream headwaters are at 37°52′12″N 90°47′40″W / 37.87000°N 90.79444°W about five miles south of Potosi and the stream flows south to southeast to its confluence with the Big River is at 37°48′42″N 90°46′20″W / 37.81167°N 90.77222°WCoordinates: 37°48′42″N 90°46′20″W / 37.81167°N 90.77222°W adjacent to Missouri Route 21 three miles north of Caledonia.