Francois Jacob
| François Jacob | |
|---|---|
 |
|
| Born |
17 June 1920 Nancy, France |
| Died | 19 April 2013 (aged 92) Paris, France |
| Citizenship | French |
| Alma mater | University of Paris |
| Known for | Operon |
| Notable awards |
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| Spouse | Lise Bloch (4 children) Geneviève Barrier (m. 1999) |
François Jacob (17 June 1920 – 19 April 2013) was a French biologist who, together with Jacques Monod, originated the idea that control of enzyme levels in all cells occurs through regulation of transcription. He shared the 1965 Nobel Prize in Medicine with Jacques Monod and André Lwoff.
Jacob was born the only child of Simon, a merchant, and Thérèse (Franck) Jacob, in Nancy, France. An inquisitive child, he learned to read at a young age. Albert Franck, Jacob’s maternal grandfather, a four-star general, was Jacob’s childhood role model. At seven he entered the Lycée Carnot, where he was schooled for the next ten years; in his autobiography he describes his impression of it: "a cage". He was antagonized by rightist youth at the Lycée Carnot around 1934. He describes his father as a "conformist in religion", while his mother and other family members important in his childhood were secular Jews; shortly after his bar mitzvah he became an atheist.
Though interested (and talented) in physics and mathematics, Jacob was horrified at the prospect of spending two additional years in "an even more draconian regime" to prepare for higher study at the Polytechnique. Instead, after observing a surgical operation that cemented his "slight interest" in medicine, he entered medical school.
During the German occupation of France—and on the heels of his mother's death—Jacob left France for Great Britain to join the war effort. Jacob, who had only completed his second year of medical studies, joined the medical company of the French 2nd Armored Division in 1940. He was injured in a German air attack in 1944 and returned to now-liberated Paris in on 1 August 1944. For his wartime service, he was awarded France's WWII highest decoration for valor, the Cross of Liberation, as well as Légion d'honneur and croix de guerre.
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