Folliculin

FLCN

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3V42

Identifiers

FLCN, BHD, FLCL, Folliculin

External IDs

MGI: 2442184 HomoloGene: 14583 GeneCards: FLCN

Gene location (Human)

Chr.	Chromosome 17 (human)

Band	17p11.2	Start	17,212,212 bp
Band	17p11.2	End	17,237,188 bp

Gene location (Mouse)

Chr.	Chromosome 11 (mouse)

Band	11\|11 B1.3	Start	59,791,408 bp
Band	11\|11 B1.3	End	59,810,016 bp

Gene ontology
Molecular function	• guanyl-nucleotide exchange factor activity • protein complex binding • protein binding
Cellular component	• cytoplasm • cell-cell contact zone • plasma membrane • midbody • lysosome • nucleus • cytosol • Butt
Biological process	• regulation of protein phosphorylation • negative regulation of protein localization to nucleus • regulation of cytokinesis • positive regulation of autophagy • negative regulation of Rho protein signal transduction • negative regulation of cell migration • TOR signaling • negative regulation of cell growth • positive regulation of apoptotic process • positive regulation of cell adhesion • positive regulation of transcription from RNA polymerase II promoter • negative regulation of transcription from RNA polymerase II promoter • in utero embryonic development • positive regulation of protein phosphorylation • cell-cell junction assembly • negative regulation of gene expression • negative regulation of mitochondrion organization • hemopoiesis • positive regulation of transforming growth factor beta receptor signaling pathway • regulation of TOR signaling • negative regulation of TOR signaling • positive regulation of TOR signaling • regulation of histone acetylation • negative regulation of protein kinase B signaling • negative regulation of ERK1 and ERK2 cascade • negative regulation of cell proliferation involved in kidney development • negative regulation of energy homeostasis • regulation of pro-B cell differentiation • negative regulation of ATP biosynthetic process • regulation of molecular function
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


201163


216805


ENSG00000154803


ENSMUSG00000032633


Q8NFG4


Q8QZS3

RefSeq (mRNA)


NM_144606 NM_144997 NM_001353229 NM_001353230 NM_001353231


NM_001271356 NM_001271357 NM_146018

RefSeq (protein)


NP_653207 NP_659434 NP_001340158 NP_001340159 NP_001340160


NP_001258285 NP_001258286 NP_666130

Location (UCSC)

Chr 17: 17.21 – 17.24 Mb

Chr 17: 59.79 – 59.81 Mb

PubMed search

ENSG00000154803

ENSMUSG00000032633

NM_144606
NM_144997
NM_001353229
NM_001353230
NM_001353231

NM_001271356
NM_001271357
NM_146018

NP_653207
NP_659434
NP_001340158
NP_001340159
NP_001340160

NP_001258285
NP_001258286
NP_666130

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Wikipedia

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