Flavin-containing monooxygenase 3

FMO3
Identifiers
Aliases	FMO3, trimethylamine monooxygenase, flavin-containing monooxygenase 3, Dimethylaniline monooxygenase [N-oxide-forming] 3, FMOII, TMAU, dJ127D3.1, flavin containing monooxygenase 3
External IDs	OMIM: 136132 MGI: 1100496 HomoloGene: 128199 GeneCards: FMO3
EC number	1.14.13.148
Gene ontology Molecular function • trimethylamine monooxygenase activity • oxidoreductase activity • N,N-dimethylaniline monooxygenase activity • NADP binding • flavin adenine dinucleotide binding • monooxygenase activity • protein binding Cellular component • integral component of membrane • organelle membrane • endoplasmic reticulum membrane • intracellular membrane-bounded organelle • endoplasmic reticulum • membrane Biological process • xenobiotic metabolic process • oxidation-reduction process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2328	14262
Ensembl	ENSG00000007933	ENSMUSG00000026691
UniProt	P31513	P97501
RefSeq (mRNA)	NM_001002294 NM_006894 NM_001319173 NM_001319174	NM_008030
RefSeq (protein)	NP_001002294 NP_001306102 NP_001306103 NP_008825	NP_032056
Location (UCSC)	Chr 1: 171.09 – 171.12 Mb	Chr 1: 162.95 – 162.98 Mb
PubMed search

2328

14262

ENSG00000007933

ENSMUSG00000026691

P31513

P97501

NM_001002294
NM_006894
NM_001319173
NM_001319174

NM_008030

NP_001002294
NP_001306102
NP_001306103
NP_008825

NP_032056

Flavin-containing monooxygenase 3 (FMO3), also known as dimethylaniline monooxygenase [N-oxide-forming] 3 and trimethylamine monooxygenase, is a flavoprotein enzyme (EC 1.14.13.148) that in humans is encoded by the FMO3 gene. This enzyme catalyzes the following chemical reaction:

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Wikipedia