Fibrinogen gamma chain

FGG
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1DUG, 1FIB, 1FIC, 1FID, 1FZA, 1FZB, 1FZC, 1FZE, 1FZF, 1FZG, 1LT9, 1LTJ, 1N86, 1N8E, 1RE3, 1RE4, 1RF0, 1RF1, 2A45, 2FFD, 2FIB, 2H43, 2HLO, 2HOD, 2HPC, 2HWL, 2OYH, 2OYI, 2Q9I, 2VDO, 2VDP, 2VDQ, 2VDR, 2VR3, 2XNX, 2XNY, 2Y7L, 2Z4E, 3BVH, 3E1I, 3FIB, 3GHG, 3H32, 3HUS, 4B60
Identifiers
Aliases	FGG
External IDs	MGI: 95526 HomoloGene: 429 GeneCards: FGG
Gene ontology Molecular function • protein binding, bridging • structural molecule activity • metal ion binding • protein binding • receptor binding • cell adhesion molecule binding • protein homodimerization activity Cellular component • cytoplasm • platelet alpha granule • blood microparticle • plasma membrane • fibrinogen complex • extracellular region • cell surface • cell cortex • extracellular exosome • platelet alpha granule lumen • external side of plasma membrane • extracellular space Biological process • hemostasis • negative regulation of endothelial cell apoptotic process • positive regulation of peptide hormone secretion • protein polymerization • positive regulation of heterotypic cell-cell adhesion • fibrinolysis • platelet degranulation • blood coagulation • cellular protein complex assembly • extracellular matrix organization • protein secretion • response to calcium ion • positive regulation of substrate adhesion-dependent cell spreading • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • positive regulation of vasoconstriction • positive regulation of protein secretion • positive regulation of ERK1 and ERK2 cascade • positive regulation of exocytosis • blood coagulation, fibrin clot formation • plasminogen activation • cell-matrix adhesion • platelet aggregation • signal transduction • platelet activation • toll-like receptor signaling pathway • platelet maturation • cellular response to interleukin-1 • cellular response to interleukin-6 • negative regulation of platelet aggregation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2266	99571
Ensembl	ENSG00000171557	ENSMUSG00000033860
UniProt	P02679	Q8VCM7
RefSeq (mRNA)	NM_021870 NM_000509	NM_133862 NM_001317105
RefSeq (protein)	NP_000500 NP_068656	NP_598623.1 NP_001304034 NP_598623
Location (UCSC)	Chr 4: 154.6 – 154.61 Mb	Chr 3: 83.01 – 83.02 Mb
PubMed search

1DUG, 1FIB, 1FIC, 1FID, 1FZA, 1FZB, 1FZC, 1FZE, 1FZF, 1FZG, 1LT9, 1LTJ, 1N86, 1N8E, 1RE3, 1RE4, 1RF0, 1RF1, 2A45, 2FFD, 2FIB, 2H43, 2HLO, 2HOD, 2HPC, 2HWL, 2OYH, 2OYI, 2Q9I, 2VDO, 2VDP, 2VDQ, 2VDR, 2VR3, 2XNX, 2XNY, 2Y7L, 2Z4E, 3BVH, 3E1I, 3FIB, 3GHG, 3H32, 3HUS, 4B60

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