Feline panleukopenia
| Feline panleukopenia virus | |
|---|---|
| Virus classification | |
| Group: | Group II (ssDNA) |
| Family: | Parvoviridae |
| Subfamily: | Parvovirinae |
| Genus: | Protoparvovirus |
| Species: | Feline panleukopenia virus |
Feline panleukopenia virus (FPV), also known as Feline infectious enteritis, Feline parvoviral enteritis, feline ataxia, feline distemper, or cat plague, is a viral infection affecting cats, both domesticated and wild feline species. It is caused by feline parvovirus, a close relative of both type 2 canine parvovirus and mink enteritis. Once contracted, it is highly contagious and can be fatal to the affected cat. The name panleukopenia comes from the low white blood cell count (leucocytes) exhibited by affected animals.
Panleukopenia is primarily spread through contact with an infected animal's bodily fluids, feces, or other fomites, as well as by fleas. It may be spread to and by cats, minks and ferrets and can be spread long distances through contact with bedding, food dishes, or even by clothing and shoes of handlers of infected animals. It is not, however, contagious or contractable by humans. Like all parvoviruses, FPV is extremely resistant to inactivation and can survive for longer than one year in a suitable environment.
The virus primarily attacks the lining of the gastrointestinal tract, causing internal ulceration and, ultimately, total sloughing of the intestinal epithelium. This results in profuse and usually bloody diarrhea, severe dehydration, malnutrition, anemia, and often death. It causes a decrease in the cat's white blood cells, thus compromising its immune system. Typically, it also causes a decrease in and platelet counts on a complete blood count. This is often key in diagnosing panleukopenia. Other symptoms include depression, lethargy, loss of appetite, fever, vomiting, loss of skin elasticity due to dehydration, and self-biting in the tail, lower back and back legs. Affected cats may sit for hours at their water bowl, although they may not drink much. Terminal cases are hypothermic and may develop septic shock and disseminated intravascular coagulation. Most panleukopenia deaths are due to secondary infections or dehydration resulting from diarrhea. This is because the virus affects the infected cat's immune system, leaving it vulnerable to secondary infection.
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