Fatty aldehyde dehydrogenase

ALDH3A2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4QGK
Identifiers
Aliases	ALDH3A2, aldehyde dehydrogenase 3 family, member A2, ALDH10, FALDH, SLS, aldehyde dehydrogenase 3 family member A2
External IDs	MGI: 1353452 HomoloGene: 55458 GeneCards: ALDH3A2
Gene location (Human) Chr. Chromosome 17 (human) Band 17p11.2 Start 19,648,136 bp End 19,677,598 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11 B2|11 37.96 cM Start 61,223,417 bp End 61,267,464 bp
Gene ontology Molecular function • long-chain-aldehyde dehydrogenase activity • long-chain-alcohol oxidase activity • aldehyde dehydrogenase [NAD(P)+ activity] • medium-chain-aldehyde dehydrogenase activity • oxidoreductase activity • aldehyde dehydrogenase (NAD) activity Cellular component • integral component of membrane • endoplasmic reticulum membrane • membrane • intracellular membrane-bounded organelle • peroxisome • endoplasmic reticulum • mitochondrion • mitochondrial inner membrane • extracellular exosome • peroxisomal membrane Biological process • peripheral nervous system development • sesquiterpenoid metabolic process • phytol metabolic process • sphingolipid biosynthetic process • cellular aldehyde metabolic process • central nervous system development • epidermis development • metabolism • oxidation-reduction process • fatty acid alpha-oxidation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	224	11671
Ensembl	ENSG00000072210	ENSMUSG00000010025
UniProt	P51648	P47740
RefSeq (mRNA)	NM_000382 NM_001031806	NM_007437 NM_001331114 NM_001331115
RefSeq (protein)	NP_000373 NP_001026976	NP_001318043 NP_001318044 NP_031463
Location (UCSC)	Chr 17: 19.65 – 19.68 Mb	Chr 17: 61.22 – 61.27 Mb
PubMed search

4QGK

224

11671

ENSG00000072210

ENSMUSG00000010025

P51648

P47740

NM_000382
NM_001031806

NM_007437
NM_001331114
NM_001331115

NP_000373
NP_001026976

NP_001318043
NP_001318044
NP_031463

Fatty aldehyde dehydrogenase (or Long-chain-aldehyde dehydrogenase) is an aldehyde dehydrogenase enzyme that in human is encoded in the ALDH3A2 gene on chromosome 17. Aldehyde dehydrogenase enzymes function to remove toxic aldehydes that are generated by the metabolism of alcohol and by lipid peroxidation.

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Wikipedia