Factor XI

F11
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1XX9, 1XXD, 1XXF, 1ZHM, 1ZHP, 1ZHR, 1ZJD, 1ZLR, 1ZMJ, 1ZML, 1ZMN, 1ZOM, 1ZPB, 1ZPC, 1ZPZ, 1ZRK, 1ZSJ, 1ZSK, 1ZSL, 1ZTJ, 1ZTK, 1ZTL, 2F83, 2FDA, 2J8J, 2J8L, 3BG8, 3SOR, 3SOS, 4CR5, 4CR9, 4CRA, 4CRB, 4CRC, 4CRD, 4CRE, 4CRF, 4CRG, 4NA7, 4NA8, 4TY6, 4TY7, 4WXI, 4X6M, 4X6N, 4X6O, 4X6P, 4Y8X, 4Y8Y, 4Y8Z, 4D7F, 5E2O, 5E2P, 4D76, 4D7G, 5EXL, 5I25, 5EXM, 5EOD, 5EXN, 5EOK
Identifiers
Aliases	F11, FXI, coagulation factor XI
External IDs	OMIM: 264900 MGI: 99481 HomoloGene: 86654 GeneCards: F11
Gene ontology Molecular function • serine-type aminopeptidase activity • peptidase activity • heparin binding • serine-type endopeptidase activity • serine-type peptidase activity • protein binding • hydrolase activity Cellular component • extracellular region • plasma membrane • extracellular exosome • membrane • extracellular space Biological process • hemostasis • blood coagulation, intrinsic pathway • plasminogen activation • regulation of blood coagulation • proteolysis • positive regulation of fibrinolysis • blood coagulation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2160	109821
Ensembl	ENSG00000088926	ENSMUSG00000031645
UniProt	P03951	Q91Y47
RefSeq (mRNA)	NM_000128 NM_019559	NM_028066
RefSeq (protein)	NP_000119	NP_082342.1 NP_082342
Location (UCSC)	Chr 4: 186.27 – 186.29 Mb	Chr 8: 45.24 – 45.26 Mb
PubMed search

1XX9, 1XXD, 1XXF, 1ZHM, 1ZHP, 1ZHR, 1ZJD, 1ZLR, 1ZMJ, 1ZML, 1ZMN, 1ZOM, 1ZPB, 1ZPC, 1ZPZ, 1ZRK, 1ZSJ, 1ZSK, 1ZSL, 1ZTJ, 1ZTK, 1ZTL, 2F83, 2FDA, 2J8J, 2J8L, 3BG8, 3SOR, 3SOS, 4CR5, 4CR9, 4CRA, 4CRB, 4CRC, 4CRD, 4CRE, 4CRF, 4CRG, 4NA7, 4NA8, 4TY6, 4TY7, 4WXI, 4X6M, 4X6N, 4X6O, 4X6P, 4Y8X, 4Y8Y, 4Y8Z, 4D7F, 5E2O, 5E2P, 4D76, 4D7G, 5EXL, 5I25, 5EXM, 5EOD, 5EXN, 5EOK

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