Factor VII

F7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4YT7, 1BF9, 1CVW, 1DAN, 1DVA, 1F7E, 1F7M, 1FAK, 1FF7, 1FFM, 1J9C, 1JBU, 1KLI, 1KLJ, 1O5D, 1QFK, 1W0Y, 1W2K, 1W7X, 1W8B, 1WQV, 1WSS, 1WTG, 1WUN, 1WV7, 1YGC, 1Z6J, 2A2Q, 2AEI, 2AER, 2B7D, 2B8O, 2BZ6, 2C4F, 2EC9, 2F9B, 2FIR, 2FLB, 2FLR, 2PUQ, 2ZP0, 2ZWL, 2ZZU, 3ELA, 3TH2, 3TH3, 3TH4, 4IBL, 4ISH, 4ISI, 4JYU, 4JYV, 4JZD, 4JZE, 4JZF, 4NA9, 4NG9, 4NGA, 4X8S, 4X8T, 4X8U, 4X8V, 4YT6, 4ZXX, 4ZXY, 4Z6A, 4ZMA, 4YLQ, 5I46
Identifiers
Aliases	F7, SPCA, coagulation factor VII
External IDs	OMIM: 613878 MGI: 109325 HomoloGene: 7710 GeneCards: F7
Gene ontology Molecular function • calcium ion binding • endopeptidase activity • glycoprotein binding • peptidase activity • protein binding • serine-type peptidase activity • receptor binding • hydrolase activity • serine-type endopeptidase activity Cellular component • vesicle • endoplasmic reticulum lumen • plasma membrane • extracellular region • Golgi lumen • extracellular space • serine-type peptidase complex Biological process • hemostasis • positive regulation of protein kinase B signaling • response to organic cyclic compound • positive regulation of cell migration • positive regulation of platelet-derived growth factor receptor signaling pathway • proteolysis • response to estrogen • positive regulation of leukocyte chemotaxis • ER to Golgi vesicle-mediated transport • response to vitamin K • signal peptide processing • positive regulation of blood coagulation • response to nutrient levels • animal organ regeneration • response to growth hormone • response to hormone • blood coagulation, extrinsic pathway • peptidyl-glutamic acid carboxylation • positive regulation of positive chemotaxis • response to thyroid hormone • protein processing • blood coagulation • response to 2,3,7,8-tetrachlorodibenzodioxine • response to estradiol • response to carbon dioxide • response to genistein • response to cholesterol • circadian rhythm • response to thyroxine • response to Thyroid stimulating hormone • response to hypoxia • response to anticoagulant • response to astaxanthin • response to thyrotropin-releasing hormone Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2155	14068
Ensembl	ENSG00000057593	ENSMUSG00000031443
UniProt	P08709	P70375
RefSeq (mRNA)	NM_000131 NM_001267554 NM_019616	NM_010172
RefSeq (protein)	NP_000122 NP_001254483 NP_062562	NP_034302.2 NP_034302
Location (UCSC)	Chr 13: 113.11 – 113.12 Mb	Chr 8: 13.03 – 13.04 Mb
PubMed search

4YT7, 1BF9, 1CVW, 1DAN, 1DVA, 1F7E, 1F7M, 1FAK, 1FF7, 1FFM, 1J9C, 1JBU, 1KLI, 1KLJ, 1O5D, 1QFK, 1W0Y, 1W2K, 1W7X, 1W8B, 1WQV, 1WSS, 1WTG, 1WUN, 1WV7, 1YGC, 1Z6J, 2A2Q, 2AEI, 2AER, 2B7D, 2B8O, 2BZ6, 2C4F, 2EC9, 2F9B, 2FIR, 2FLB, 2FLR, 2PUQ, 2ZP0, 2ZWL, 2ZZU, 3ELA, 3TH2, 3TH3, 3TH4, 4IBL, 4ISH, 4ISI, 4JYU, 4JYV, 4JZD, 4JZE, 4JZF, 4NA9, 4NG9, 4NGA, 4X8S, 4X8T, 4X8U, 4X8V, 4YT6, 4ZXX, 4ZXY, 4Z6A, 4ZMA, 4YLQ, 5I46

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