FXR2

FXR2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3H8Z
Identifiers
Aliases	FXR2, FMR1L2, FXR2P, FMR1 autosomal homolog 2
External IDs	MGI: 1346074 HomoloGene: 21014 GeneCards: FXR2
Gene ontology Molecular function • protein heterodimerization activity • nucleic acid binding • protein binding • mRNA binding • protein homodimerization activity • identical protein binding • RNA binding Cellular component • polysome • cytosolic large ribosomal subunit • extracellular exosome • membrane • Q40260 • cytoplasm • cytosol Biological process • negative regulation of translation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9513	23879
Ensembl	ENSG00000129245	ENSMUSG00000018765
UniProt	P51116	Q9WVR4 Q6P5B5
RefSeq (mRNA)	NM_004860	NM_011814
RefSeq (protein)	NP_004851	NP_035944
Location (UCSC)	Chr 17: 7.59 – 7.61 Mb	Chr 11: 69.63 – 69.65 Mb
PubMed search

3H8Z

9513

23879

ENSG00000129245

ENSMUSG00000018765

P51116

Q9WVR4
Q6P5B5

NM_004860

NM_011814

NP_004851

NP_035944

Fragile X mental retardation syndrome-related protein 2 is a protein that in humans is encoded by the FXR2 gene.

The protein encoded by this gene is an RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.

FXR2 has been shown to interact with:

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Wikipedia