FTO gene

FTO

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3LFM, 4IDZ, 4IE0, 4IE4, 4IE5, 4IE6, 4IE7, 4CXW, 4CXX, 4CXY, 4QHO, 4QKN, 4ZS3, 4ZS2

Identifiers

FTO, ALKBH9, GDFD, BMIQ14, fat mass and obesity associated, alpha-ketoglutarate dependent dioxygenase

External IDs

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• oxidative DNA demethylase activity • dioxygenase activity • metal ion binding • DNA-N1-methyladenine dioxygenase activity • oxidoreductase activity • ferrous iron binding • RNA N6-methyladenosine dioxygenase activity • oxidative RNA demethylase activity
Cellular component	• nuclear speck • nucleus • nucleoplasm
Biological process	• regulation of multicellular organism growth • regulation of respiratory system process • regulation of white fat cell proliferation • cellular response to DNA damage stimulus • oxidative demethylation • oxidative single-stranded RNA demethylation • regulation of lipid storage • RNA repair • adipose tissue development • DNA demethylation • regulation of brown fat cell differentiation • temperature homeostasis • oxidative single-stranded DNA demethylation • oxidation-reduction process • DNA repair • DNA dealkylation involved in DNA repair
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


79068


26383


ENSG00000140718


ENSMUSG00000055932


Q9C0B1


Q8BGW1

RefSeq (mRNA)


NM_001080432


NM_011936

RefSeq (protein)


NP_001073901


NP_036066

Location (UCSC)

PubMed search