FSHB

FSHB
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1FL7, 1XWD, 4AY9, 4MQW
Identifiers
Aliases	FSHB, HH24, follicle stimulating hormone beta subunit, Follitropin subunit beta
External IDs	MGI: 95582 HomoloGene: 430 GeneCards: FSHB
Gene ontology Molecular function • follicle-stimulating hormone activity • protein binding • hormone activity Cellular component • extracellular exosome • cytoplasm • extracellular region • extracellular space Biological process • progesterone biosynthetic process • female gamete generation • positive regulation of bone resorption • regulation of osteoclast differentiation • transforming growth factor beta receptor signaling pathway • positive regulation of cell migration • positive regulation of transcription from RNA polymerase II promoter • female pregnancy • positive regulation of cell proliferation • ovarian follicle development • Sertoli cell proliferation • signal transduction • peptide hormone processing • positive regulation of gene expression • cell-cell signaling • hormone-mediated signaling pathway • follicle-stimulating hormone signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2488	14308
Ensembl	ENSG00000131808	ENSMUSG00000027120
UniProt	P01225	Q60687
RefSeq (mRNA)	NM_000510 NM_001018080	NM_008045
RefSeq (protein)	NP_000501 NP_001018090	NP_032071.1 NP_032071
Location (UCSC)	Chr 11: 30.23 – 30.24 Mb	Chr 2: 107.06 – 107.06 Mb
PubMed search

1FL7, 1XWD, 4AY9, 4MQW

2488

14308

ENSG00000131808

ENSMUSG00000027120

P01225

Q60687

NM_000510
NM_001018080

NM_008045

NP_000501
NP_001018090

NP_032071.1
NP_032071

Follitropin subunit beta also known as follicle-stimulating hormone beta subunit (FSH-B) is a protein that in humans is encoded by the FSHB gene. Alternative splicing results in two transcript variants encoding the same protein.

The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production.

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Wikipedia