FOLR1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4KM6, 4KM7, 4KMX, 4LRH

Identifiers

Aliases

FOLR1, FBP, FOLR, Folate receptor 1, folate receptor 1 (adult)

External IDs

MGI: 95568 HomoloGene: 7322 GeneCards: FOLR1

Gene ontology
Molecular function	• methotrexate binding • drug binding • receptor activity • folic acid receptor activity • folic acid transporter activity • folic acid binding
Cellular component	• anchored component of external side of plasma membrane • extracellular region • brush border • clathrin-coated vesicle • ER to Golgi transport vesicle membrane • anchored component of membrane • Golgi membrane • nucleus • integral component of plasma membrane • apical plasma membrane • membrane • cell surface • endoplasmic reticulum membrane • brush border membrane • basolateral plasma membrane • plasma membrane • cytoplasmic vesicle • endosome • endoplasmic reticulum-Golgi intermediate compartment membrane • anchored component of plasma membrane • extracellular exosome • transport vesicle
Biological process	• receptor-mediated endocytosis • cellular response to folic acid • neural crest cell migration involved in heart formation • axon regeneration • COPII vesicle coating • ER to Golgi vesicle-mediated transport • heart looping • cardiac neural crest cell migration involved in outflow tract morphogenesis • pharyngeal arch artery morphogenesis • folic acid metabolic process • regulation of transforming growth factor beta receptor signaling pathway • response to axon injury • regulation of canonical Wnt signaling pathway • anterior neural tube closure • folic acid transport • transport
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


2348


14275

Ensembl


ENSG00000110195


ENSMUSG00000001827

UniProt


P15328


P35846

RefSeq (mRNA)


NM_016730 NM_000802 NM_016724 NM_016725 NM_016729


NM_001252552 NM_001252553 NM_001252554 NM_008034

RefSeq (protein)


NP_000793 NP_057936 NP_057937 NP_057941


NP_001239481 NP_001239482 NP_001239483 NP_032060

Location (UCSC)

Chr 11: 72.19 – 72.2 Mb

Chr 7: 101.86 – 101.87 Mb

PubMed search

4KM6, 4KM7, 4KMX, 4LRH

NM_016730
NM_000802
NM_016724
NM_016725
NM_016729

NM_001252552
NM_001252553
NM_001252554
NM_008034

NP_000793
NP_057936
NP_057937
NP_057941

...
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