FHIT

FHIT

Protein FHIT PDB 1fhi.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1FHI, 2FHI, 2FIT, 5FIT, 3FIT, 1FIT, 4FIT, 6FIT

Identifiers

FHIT, AP3Aase, FRA3B, fragile histidine triad

External IDs

MGI: 1277947 HomoloGene: 21661 GeneCards: FHIT

Genetically Related Diseases

myopia, orofacial cleft, Asperger syndrome, attention deficit hyperactivity disorder

Gene ontology
Molecular function	• bis(5'-adenosyl)-triphosphatase activity • nucleotide binding • catalytic activity • hydrolase activity • protein binding • ubiquitin protein ligase binding • identical protein binding
Cellular component	• cytoplasm • cytosol • extracellular exosome • mitochondrion • nucleus • fibrillar center • plasma membrane
Biological process	• negative regulation of proteasomal ubiquitin-dependent protein catabolic process • purine nucleotide metabolic process • regulation of transcription, DNA-templated • nucleotide metabolic process • transcription, DNA-templated • intrinsic apoptotic signaling pathway by p53 class mediator • apoptotic process
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE FHIT gnf1h04116 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


2272


14198


ENSG00000189283


ENSMUSG00000060579


P49789


O89106

RefSeq (mRNA)


NM_001166243 NM_002012 NM_001320899 NM_001320900 NM_001320901


NM_010210 NM_001308285 NM_001308286

RefSeq (protein)


NP_001159715 NP_001307828 NP_001307829 NP_001307830 NP_002003


NP_001295215.1 NP_034340.1 NP_001295214 NP_001295215 NP_034340

Location (UCSC)

Chr 3: 59.75 – 61.25 Mb

Chr 14: 9.55 – 11.16 Mb

PubMed search

1FHI, 2FHI, 2FIT, 5FIT, 3FIT, 1FIT, 4FIT, 6FIT

ENSG00000189283

ENSMUSG00000060579

NM_001166243
NM_002012
NM_001320899
NM_001320900
NM_001320901

NM_010210
NM_001308285
NM_001308286

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Wikipedia

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