FGFR4

FGFR4

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4QQ5, 4QQC, 4QQJ, 4QQT, 4QRC, 4R6V, 4TYE, 4TYG, 4TYI, 4TYJ, 4UXQ, 4XCU

Identifiers

FGFR4, CD334, JTK2, TKF, fibroblast growth factor receptor 4

External IDs

MGI: 95525 HomoloGene: 20461 GeneCards: FGFR4

Gene ontology
Molecular function	• transferase activity • nucleotide binding • protein kinase activity • heparin binding • kinase activity • protein binding • transmembrane receptor protein tyrosine kinase activity • protein tyrosine kinase activity • fibroblast growth factor binding • fibroblast growth factor-activated receptor activity • ATP binding • Ras guanyl-nucleotide exchange factor activity • phosphatidylinositol-4,5-bisphosphate 3-kinase activity • 1-phosphatidylinositol-3-kinase activity
Cellular component	• integral component of membrane • endosome • Golgi apparatus • membrane • cell-cell junction • plasma membrane • integral component of plasma membrane • transport vesicle • extracellular region • endoplasmic reticulum • cytoplasm
Biological process	• regulation of cholesterol homeostasis • glucose homeostasis • phosphorylation • phosphate ion homeostasis • response to bile acid • regulation of extracellular matrix disassembly • MAPK cascade • regulation of bile acid biosynthetic process • fibroblast growth factor receptor signaling pathway • regulation of lipid metabolic process • protein phosphorylation • positive regulation of gene expression • positive regulation of cell proliferation • positive regulation of DNA biosynthetic process • positive regulation of ERK1 and ERK2 cascade • positive regulation of proteolysis • protein autophosphorylation • peptidyl-tyrosine phosphorylation • cell migration • phosphatidylinositol-mediated signaling • positive regulation of GTPase activity • phosphatidylinositol phosphorylation • positive regulation of catalytic activity • regulation of phosphatidylinositol 3-kinase signaling • phosphatidylinositol-3-phosphate biosynthetic process
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE FGFR4 204579 at fs.png

PBB GE FGFR4 211237 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


2264


14186


ENSG00000160867


ENSMUSG00000005320


P22455


Q03142

RefSeq (mRNA)


NM_001291980 NM_002011 NM_022963 NM_213647


NM_008011

RefSeq (protein)


NP_001278909 NP_002002 NP_075252 NP_998812


NP_032037.2 NP_032037

Location (UCSC)

Chr 5: 177.09 – 177.1 Mb

Chr 13: 55.15 – 55.17 Mb

PubMed search

4QQ5, 4QQC, 4QQJ, 4QQT, 4QRC, 4R6V, 4TYE, 4TYG, 4TYI, 4TYJ, 4UXQ, 4XCU

ENSG00000160867

ENSMUSG00000005320

NM_001291980
NM_002011
NM_022963
NM_213647

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Wikipedia

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