FGF8

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2FDB

Identifiers

Aliases

FGF8, AIGF, FGF-8, HBGF-8, HH6, KAL6, fibroblast growth factor 8

External IDs

MGI: 99604 HomoloGene: 7715 GeneCards: FGF8

Gene ontology
Molecular function	• type 1 fibroblast growth factor receptor binding • type 2 fibroblast growth factor receptor binding • growth factor activity • fibroblast growth factor receptor binding • chemoattractant activity • protein tyrosine kinase activity • 1-phosphatidylinositol-3-kinase activity • phosphatidylinositol-4,5-bisphosphate 3-kinase activity • Ras guanyl-nucleotide exchange factor activity
Cellular component	• extracellular region • intracellular • external side of plasma membrane • extracellular space
Biological process	• negative regulation of neuron apoptotic process • cell migration involved in mesendoderm migration • male genitalia development • epithelial to mesenchymal transition involved in endocardial cushion formation • outflow tract morphogenesis • embryonic heart tube development • mesonephros development • heart looping • forebrain neuron development • blood vessel remodeling • central nervous system neuron development • positive regulation of ERK1 and ERK2 cascade • metanephros development • cell proliferation in forebrain • positive regulation of mitotic nuclear division • gonad development • pharyngeal system development • branching involved in salivary gland morphogenesis • apoptotic process • dopaminergic neuron differentiation • cell fate commitment • limb morphogenesis • kidney development • lung development • anatomical structure morphogenesis • signal transduction involved in regulation of gene expression • regulation of odontogenesis of dentin-containing tooth • response to oxidative stress • embryo development ending in birth or egg hatching • forebrain morphogenesis • heart development • telencephalon development • branching involved in ureteric bud morphogenesis • midbrain-hindbrain boundary development • branching involved in blood vessel morphogenesis • thyroid-stimulating hormone-secreting cell differentiation • positive chemotaxis • mesodermal cell migration • cell differentiation • dorsal/ventral axon guidance • corticotropin hormone secreting cell differentiation • organ induction • neural plate morphogenesis • positive regulation of organ growth • negative regulation of apoptotic process • BMP signaling pathway • outflow tract septum morphogenesis • odontogenesis • thyroid gland development • pallium development • gastrulation • canonical Wnt signaling pathway • phosphatidylinositol-mediated signaling • subpallium development • lung morphogenesis • response to organic cyclic compound • otic vesicle formation • forebrain dorsal/ventral pattern formation • heart morphogenesis • aorta morphogenesis • generation of neurons • MAPK cascade • neuroepithelial cell differentiation • multicellular organism development • fibroblast growth factor receptor signaling pathway • positive regulation of gene expression • negative regulation of cardiac muscle tissue development • determination of left/right symmetry • inner ear morphogenesis • positive regulation of cell proliferation • bone development • motor neuron axon guidance • positive regulation of cell division • response to drug • embryonic hindlimb morphogenesis • positive regulation of GTPase activity • phosphatidylinositol phosphorylation • phosphatidylinositol-3-phosphate biosynthetic process • peptidyl-tyrosine phosphorylation • regulation of phosphatidylinositol 3-kinase signaling • positive regulation of cell differentiation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


2253


14179

Ensembl


ENSG00000107831


ENSMUSG00000025219

UniProt


P55075


P37237

RefSeq (mRNA)


NM_001206389 NM_006119 NM_033163 NM_033164 NM_033165


NM_001166361 NM_001166362 NM_001166363 NM_010205

RefSeq (protein)


NP_001193318 NP_006110 NP_149353 NP_149354 NP_149355

NP_001159834.1 NP_001159835.1 NP_034335.1 NP_001159833 NP_001159834
NP_001159835 NP_034335

Location (UCSC)

Chr 10: 101.77 – 101.78 Mb

Chr 19: 45.74 – 45.74 Mb

PubMed search

NM_001206389
NM_006119
NM_033163
NM_033164
NM_033165

NM_001166361
NM_001166362
NM_001166363
NM_010205

NP_001193318
NP_006110
NP_149353
NP_149354
NP_149355

...
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