FBLN4

EFEMP2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2KL7
Identifiers
Aliases	EFEMP2, ARCL1B, FBLN4, MBP1, UPH1, EGF containing fibulin like extracellular matrix protein 2
External IDs	MGI: 1891209 HomoloGene: 32339 GeneCards: EFEMP2
Gene location (Human) Chr. Chromosome 11 (human) Band 11q13.1 Start 65,866,441 bp End 65,873,592 bp
Gene location (Mouse) Chr. Chromosome 19 (mouse) Band 19|19 A Start 5,473,973 bp End 5,481,853 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • calcium ion binding • extracellular matrix structural constituent • protein binding Cellular component • extracellular vesicle • extracellular region • basement membrane • extracellular exosome • extracellular space Biological process • elastic fiber assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	30008	58859
Ensembl	ENSG00000172638	ENSMUSG00000024909
UniProt	O95967	Q9WVJ9
RefSeq (mRNA)	NM_016938	NM_001164352 NM_021474
RefSeq (protein)	NP_058634	NP_001157824 NP_067449
Location (UCSC)	Chr 11: 65.87 – 65.87 Mb	Chr 11: 5.47 – 5.48 Mb
PubMed search

2KL7

30008

58859

ENSG00000172638

ENSMUSG00000024909

O95967

Q9WVJ9

NM_016938

NM_001164352
NM_021474

NP_058634

NP_001157824
NP_067449

EGF-containing fibulin-like extracellular matrix protein 2 is a protein that in humans is encoded by the EFEMP2 gene.

A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. EFEMP2 (also known as fibulin-4) contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is widely expressed in a range of adult and fetal tissues.

EFEMP2 has been shown to interact with P53.

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Wikipedia