"Exogenesis: Symphony", commonly known as simply "Exogenesis", is a song by English alternative rock band Muse, featured on their 2009 fifth studio album The Resistance. Written by lead vocalist, guitarist and pianist Matthew Bellamy over the course of a number of years, the song is presented as a symphony in three movements entitled "Overture", "Cross-Pollination" and "Redemption", respectively, each occupying a separate track at the end of the album and spanning nearly 13 minutes in total. "Exogenesis" was released as a single in the United States on 17 April 2010, with 500 copies to be made available by import in the United Kingdom through the band's official website.

On 30 October 2012, an official music video directed by Japanese comedian Tekken was released for Redemption, the third part of the Exogenesis Symphony.

A song in the long, symphonic style of "Exogenesis" was first hinted at as a possible inclusion for Muse's fifth studio album in early 2008, when British music magazine NME quoted Bellamy as revealing that "I think on the next album I’d like to do at least one 15-minute space rock solo." This idea was later discussed further and in a more extreme sense, when Bellamy suggested that the band may reject the conventional album format in favour of releasing a series of singles, or indeed "one 50-minute symphony."

As the band confirmed that recording had begun for the album in late 2008, Bellamy explained more about the symphonic song, which he revealed would be in three parts on the album:

With the presence of "Exogenesis", among other songs, Bellamy hinted at the classical direction taken by the band in writing and recording The Resistance, describing the record as "A symphonic album" and joking that "We'll be knocking on Classic FM's door, you know?"

Speaking for the iTunes LP feature for The Resistance, Bellamy said the following about the inspirations and meanings of "Exogenesis":

...
Wikipedia