Evolutionarily significant unit

An evolutionarily significant unit (ESU) is a population of organisms that is considered distinct for purposes of conservation. Delineating ESUs is important when considering conservation action. This term can apply to any species, subspecies, geographic race, or population. Often the term "species" is used rather than ESU, even when an ESU is more technically considered a subspecies or variety rather than a biological species proper. In marine animals the term "stock" is often used as well.

Definitions of an ESU generally include at least one of the following criteria:

Criterion 2 considers the gene flow between populations, measured by F_ST. A high degree of differentiation at neutral markers (differences in allele frequencies) implies a lack of gene flow, showing that random drift has occurred in isolation from other populations. Very few migrants per generation are needed to prevent strong differentiation of neutral markers. Even a single migrant per generation may be enough for neutral markers to show gene flow between populations, making it difficult to differentiate the populations through neutral markers.

Criterion 3 does not consider neutral genetic markers, instead looking at locally adapted traits of the population. Local adaptations may be present even with some gene flow from other populations, and even when there is little differentiation at neutral markers among ESUs. Reciprocal transplantation experiments are necessary to test for genetic differentiation for phenotypic traits, and differences in selection gradients across habitats. Such experiments are generally more difficult than the fixation index tests of criterion 2, and may be impossible for very rare or endangered species.

For example, Cryan's buckmoth (Hemileuca maia) feeds only on the herb Menyanthes trifoliata, commonly known as buckbean, and while indistinguishable morphologically from related buckmoths, and not differentiated at the genetic markers tested, the moth is highly adapted to its host plant, having 100% survivorship on Menyanthes, while close genetic relatives all died when reared on the plant. In this case gene flow was sufficient to reduce differentiation at neutral markers, but did not prevent local host adaptation.

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