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Eric J. Nestler

Eric J. Nestler
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Eric J. Nestler, M.D., Ph.D., is the Nash Family Professor of Neuroscience, Chairman of the Department of Neuroscience and Director of the Friedman Brain Institute at the Mount Sinai Medical Center in New York. His focus in neuropsychopharmacology concentrates on forming a molecular approach to psychiatry and furthering the understanding of the molecular basis of both depression and drug addiction, using animal models to study the way drug use or stress affects the brain. His addiction research largely centers around ΔFosB (a master control protein that induces addiction) and associated epigenetic remodeling in the medium spiny neurons of the nucleus accumbens.

Nestler is the author (with Dennis S. Charney) of Neurobiology of Mental Illness (), of Molecular Neuropharmacology (with Steven E. Hyman and Robert C. Malenka; ), and more than 450 chapters and peer-reviewed publications. He is active in seven research projects funded by the National Institute on Drug Abuse and the National Institute of Mental Health.

Nestler is a graduate of Herricks High School in New Hyde Park, New York. He received his B.A., his Ph.D. and his M.D. from Yale University. He completed his residency in psychiatry at both McLean Hospital in Massachusetts and Yale in 1987.


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