Epithelial membrane antigen

MUC1

Available structures

Human UniProt search: PDBe RCSB

List of PDB id codes
1SM3, 2ACM

Identifiers

Aliases

MUC1, ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, mucin 1, cell surface associated

External IDs

HomoloGene: 136477 GeneCards: MUC1

Gene ontology
Molecular function	• protein binding • transcription cofactor activity • RNA polymerase II core promoter proximal region sequence-specific DNA binding • p53 binding
Cellular component	• extracellular region • cytoplasm • integral component of membrane • nucleus • Golgi lumen • integral component of plasma membrane • apical plasma membrane • membrane • nuclear chromatin • vesicle • extracellular exosome • extracellular space • plasma membrane
Biological process	• positive regulation of histone H4 acetylation • regulation of transcription from RNA polymerase II promoter in response to stress • DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest • negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator • negative regulation of cell adhesion mediated by integrin • DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator • positive regulation of transcription from RNA polymerase II promoter in response to stress • O-glycan processing • negative regulation of transcription by competitive promoter binding • stimulatory C-type lectin receptor signaling pathway
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


4582


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Ensembl


ENSG00000185499


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UniProt


P15941 Q7Z551


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RefSeq (mRNA)

NM_001018016 NM_001018017 NM_001018021 NM_001044390 NM_001044391
NM_001044392 NM_001044393 NM_001204285 NM_001204286 NM_001204287 NM_001204288 NM_001204289 NM_001204290 NM_001204291 NM_001204292 NM_001204293 NM_001204294 NM_001204295 NM_001204296 NM_001204297 NM_002456 NM_182741


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RefSeq (protein)

NP_001018016 NP_001018017 NP_001037855 NP_001037856 NP_001037857
NP_001037858 NP_001191214 NP_001191215 NP_001191216 NP_001191217 NP_001191218 NP_001191219 NP_001191220 NP_001191221 NP_001191222 NP_001191223 NP_001191224 NP_001191225 NP_001191226 NP_002447 NP_001191217.1 NP_001191225.1 NP_001037856.1


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Location (UCSC)

Chr 1: 155.19 – 155.19 Mb

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PubMed search

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NM_001044392
NM_001044393
NM_001204285
NM_001204286
NM_001204287
NM_001204288
NM_001204289
NM_001204290
NM_001204291
NM_001204292
NM_001204293
NM_001204294
NM_001204295
NM_001204296
NM_001204297
NM_002456
NM_182741

...
Wikipedia