Emma Vyssotsky (October 23, 1894 – May 12, 1975), born Emma T. R. Williams in Media, Pennsylvania was an American astronomer.
She received a Ph.D. in astronomy from Harvard College in 1930. She spent her career at the McCormick Observatory of the University of Virginia, where her speciality was the motion of stars and the kinematics of the Milky Way.
She married the Russian-born astronomer Alexander N. Vyssotsky in 1929. They had one son, Victor A. Vyssotsky (a mathematician and computer scientist), who was involved in the Multics project and creator of the Darwin computer game.
She was awarded the Annie J. Cannon Award in Astronomy by the American Astronomical Society in 1946.