Elizabeth Frances Coxen née Isaac (1825–1906) was an Australian naturalist and meteorologist.
After the death of her husband, Charles Coxen, she became the first female elected a member of the Royal Society of Queensland.
Elizabeth Coxen died on 10 August 1906 and was buried with her husband in the cemetery of Christ Church in Tingalpa.
Her friends commissioned a plaque commemorating her at St John the Baptist Anglican Church at Bulimba.