The Eastman Business College was a business school located in Poughkeepsie, New York, United States.
The college was founded in 1859 by Harvey G. Eastman, and was for a time one of the largest commercial schools in the United States.
Rather than merely being a theoretical school, students gained practical experience in the business arts by actually performing the tasks that would be expected of them in their working careers, a novel approach at the time.
The 1898 catalog of the Eastman Business College and its affiliated school, the New York Business Institute, stated, "These schools do not receive students of the Negro Race".
In 1905 S. V. Daniels, a 17-year-old from St. Thomas, withdrew from the main college following the petition of 160 southern students alleging that he was partially of African descent, and transferred to the Harlem branch.
The college closed on June 10, 1931.