EPRS

EPRS
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1FYJ, 4HVC, 4K86, 4K87, 4K88, 5A34, 5BMU, 5A1N, 5A5H
Identifiers
Aliases	EPRS, EARS, GLUPRORS, PARS, QARS, QPRS, PIG32, glutamyl-prolyl-tRNA synthetase
External IDs	MGI: 97838 HomoloGene: 5870 GeneCards: EPRS
Gene ontology Molecular function • nucleotide binding • protein binding • RNA stem-loop binding • ligase activity, forming aminoacyl-tRNA and related compounds • ATP binding • catalytic activity • ligase activity • aminoacyl-tRNA ligase activity • GTPase binding • RNA binding • proline-tRNA ligase activity • glutamate-tRNA ligase activity Cellular component • intracellular ribonucleoprotein complex • cytoplasm • membrane • cytosol • GAIT complex • aminoacyl-tRNA synthetase multienzyme complex Biological process • protein complex assembly • regulation of translation • tRNA aminoacylation • metabolic process • translation • tRNA aminoacylation for protein translation • negative regulation of translation • cellular response to interferon-gamma • prolyl-tRNA aminoacylation • glutamyl-tRNA aminoacylation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2058	107508
Ensembl	ENSG00000136628	ENSMUSG00000026615
UniProt	P07814	Q8CGC7
RefSeq (mRNA)	NM_004446	NM_029735
RefSeq (protein)	NP_004437	NP_084011.1 NP_084011
Location (UCSC)	Chr 1: 219.97 – 220.05 Mb	Chr 1: 185.36 – 185.43 Mb
PubMed search

1FYJ, 4HVC, 4K86, 4K87, 4K88, 5A34, 5BMU, 5A1N, 5A5H

2058

107508

ENSG00000136628

ENSMUSG00000026615

P07814

Q8CGC7

NM_004446

NM_029735

NP_004437

NP_084011.1
NP_084011

Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene.

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Wikipedia