EPH receptor A2

EPHA2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1MQB, 2E8N, 2K9Y, 2KSO, 2X10, 2X11, 3C8X, 3CZU, 3FL7, 3HEI, 3HPN, 3KKA, 3MBW, 3MX0, 3SKJ, 4P2K, 4PDO, 4TRL, 5EK7
Identifiers
Aliases	EPHA2, Epha2, AW545284, Eck, Myk2, Sek-2, Sek2, ARCC2, CTPA, CTPP1, CTRCT6, EPH receptor A2, ECK
External IDs	MGI: 95278 HomoloGene: 20929 GeneCards: EPHA2
Gene ontology Molecular function • nucleotide binding • protein kinase activity • transferase activity • kinase activity • protein binding • protein tyrosine kinase activity • ATP binding • ephrin receptor activity • transmembrane receptor protein tyrosine kinase activity • cadherin binding Cellular component • integral component of membrane • cell projection • membrane • ruffle membrane • cell surface • cell junction • lamellipodium membrane • leading edge membrane • focal adhesion • integral component of plasma membrane • intracellular • plasma membrane • lamellipodium Biological process • regulation of lamellipodium assembly • skeletal system development • negative regulation of protein kinase B signaling • cell differentiation • regulation of cell adhesion mediated by integrin • protein kinase B signaling • activation of GTPase activity • phosphorylation • transmembrane receptor protein tyrosine kinase signaling pathway • keratinocyte differentiation • positive regulation of establishment of protein localization to plasma membrane • vasculogenesis • multicellular organism development • protein phosphorylation • cell adhesion • blood vessel development • notochord morphogenesis • notochord cell development • angiogenesis • intrinsic apoptotic signaling pathway in response to DNA damage • neural tube development • neuron differentiation • notochord formation • regulation of ERK1 and ERK2 cascade • cell chemotaxis • post-anal tail morphogenesis • axial mesoderm formation • response to growth factor • viral process • cell migration • apoptotic process • peptidyl-tyrosine phosphorylation • osteoclast differentiation • osteoblast differentiation • regulation of angiogenesis • regulation of blood vessel endothelial cell migration • ephrin receptor signaling pathway • lens fiber cell morphogenesis • mammary gland epithelial cell proliferation • bone remodeling • branching involved in mammary gland duct morphogenesis • negative regulation of cytokine production • defense response to Gram-positive bacterium • negative regulation of lymphangiogenesis • blood vessel endothelial cell proliferation involved in sprouting angiogenesis • pericyte cell differentiation • negative regulation of angiogenesis • inflammatory response • negative regulation of chemokine production • blood vessel morphogenesis • cAMP metabolic process • cell motility Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1969	13836
Ensembl	ENSG00000142627	ENSMUSG00000006445
UniProt	P29317	Q03145
RefSeq (mRNA)	NM_004431 NM_001329090	NM_010139
RefSeq (protein)	NP_001316019 NP_004422	NP_034269.2 NP_034269
Location (UCSC)	Chr 1: 16.12 – 16.16 Mb	Chr 4: 141.3 – 141.33 Mb
PubMed search

1MQB, 2E8N, 2K9Y, 2KSO, 2X10, 2X11, 3C8X, 3CZU, 3FL7, 3HEI, 3HPN, 3KKA, 3MBW, 3MX0, 3SKJ, 4P2K, 4PDO, 4TRL, 5EK7

1969

13836

ENSG00000142627

ENSMUSG00000006445

P29317

...
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