EIF5A

EIF5A

Protein EIF5A PDB 1FH4.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3CPF, 5DLQ

Identifiers

EIF5A, EIF-5A, EIF5A1, eIF5AI, eukaryotic translation initiation factor 5A

External IDs

MGI: 106248 HomoloGene: 133803 GeneCards: EIF5A

Gene ontology
Molecular function	• protein N-terminus binding • ribosome binding • translation elongation factor activity • protein binding • RNA binding • U6 snRNA binding
Cellular component	• cytoplasm • cytosol • endoplasmic reticulum membrane • membrane • nuclear pore • annulate lamellae • endoplasmic reticulum • extracellular exosome • nucleus • dendrite • neuronal cell body
Biological process	• mRNA transport • translation • positive regulation of translational elongation • translational elongation • mRNA export from nucleus • peptidyl-lysine modification to peptidyl-hypusine • nucleocytoplasmic transport • protein export from nucleus • positive regulation of cell proliferation • transport • protein transport • translational frameshifting • positive regulation of translational termination • apoptotic process • positive regulation of cytosolic calcium ion concentration • aging • positive regulation of cardiac muscle cell apoptotic process • positive regulation of apoptotic process • negative regulation of apoptotic process • positive regulation of muscle cell differentiation • cellular response to thyroid hormone stimulus • positive regulation of reactive oxygen species metabolic process
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE EIF5A 201122 x at fs.png

PBB GE EIF5A 201123 s at fs.png

PBB GE EIF5A 213753 x at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


1984


276770


ENSG00000132507


ENSMUSG00000078812


P63241


P63242

RefSeq (mRNA)


NM_001143760 NM_001143761 NM_001143762 NM_001970

NM_001166589 NM_001166590 NM_001166591 NM_001166592 NM_001166593
NM_001166594 NM_001166595 NM_001166596 NM_181582

RefSeq (protein)


NP_001137232 NP_001137233 NP_001137234 NP_001961

NP_001160061.1 NP_001160062.1 NP_001160063.1 NP_001160064.1 NP_001160065.1
NP_001160066.1 NP_001160067.1 NP_001160068.1 NP_853613.1 NP_001160061 NP_001160062 NP_001160063 NP_001160064 NP_001160065 NP_001160066 NP_001160067 NP_001160068 NP_853613

Location (UCSC)

Chr 17: 7.31 – 7.31 Mb

Chr 11: 69.92 – 69.92 Mb

PubMed search

ENSG00000132507

ENSMUSG00000078812

NM_001143760
NM_001143761
NM_001143762
NM_001970

NM_001166594
NM_001166595
NM_001166596
NM_181582

NP_001137232
NP_001137233
NP_001137234
NP_001961

NP_001160066.1
NP_001160067.1
NP_001160068.1
NP_853613.1
NP_001160061
NP_001160062
NP_001160063
NP_001160064
NP_001160065
NP_001160066
NP_001160067
NP_001160068
NP_853613

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Wikipedia

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