EIF4E

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1IPB, 1IPC, 1WKW, 2GPQ, 2V8W, 2V8X, 2V8Y, 2W97, 3AM7, 3TF2, 3U7X, 4AZA, 4BEA, 4DT6, 4DUM, 4TPW, 4TQB, 4TQC, 4UED, 5ABI

Identifiers

EIF4E, eukaryotic translation initiation factor 4E, AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E

External IDs

Gene ontology
Molecular function	• translation initiation factor activity • eukaryotic initiation factor 4G binding • protein binding • enzyme binding • RNA cap binding • repressing transcription factor binding • RNA 7-methylguanosine cap binding • RNA binding
Cellular component	• cytoplasm • chromatoid body • RISC complex • P-body • protein complex • mRNA cap binding complex • perinuclear region of cytoplasm • cytoplasmic stress granule • eukaryotic translation initiation factor 4F complex • extracellular exosome • cytosol
Biological process	• nuclear-transcribed mRNA poly(A) tail shortening • negative regulation of translation • negative regulation of neuron differentiation • lung development • G1/S transition of mitotic cell cycle • positive regulation of mitotic cell cycle • behavioral fear response • mRNA export from nucleus • stem cell population maintenance • translational initiation • viral process • regulation of translation • RNA export from nucleus • translation • negative regulation of autophagy • cellular response to dexamethasone stimulus
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


1977


13684


ENSG00000151247


ENSMUSG00000028156


P06730


P63073

RefSeq (mRNA)


NM_001130678 NM_001130679 NM_001968 NM_001331017


NM_007917 NM_001313980

RefSeq (protein)


NP_001124150 NP_001124151 NP_001317946 NP_001959


NP_031943.3 NP_001300909 NP_031943

Location (UCSC)

PubMed search