EIF4B

EIF4B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1WI8, 2J76
Identifiers
Aliases	EIF4B, EIF-4B, PRO1843, eukaryotic translation initiation factor 4B
External IDs	MGI: 95304 HomoloGene: 83162 GeneCards: EIF4B
Gene ontology Molecular function • protein binding • nucleic acid binding • ribosomal small subunit binding • helicase activity • RNA strand-exchange activity • RNA strand annealing activity • RNA binding • translation initiation factor activity Cellular component • cytosol • eukaryotic translation initiation factor 4F complex • polysome Biological process • nuclear-transcribed mRNA poly(A) tail shortening • regulation of translational initiation • cytoplasmic translation • formation of translation preinitiation complex • eukaryotic translation initiation factor 4F complex assembly • translation • translational initiation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1975	75705
Ensembl	ENSG00000063046	ENSMUSG00000058655
UniProt	P23588	Q8BGD9
RefSeq (mRNA)	NM_001300821 NM_001417 NM_018507 NM_001330654	NM_145625
RefSeq (protein)	NP_001287750 NP_001317583 NP_001408	NP_663600.2 NP_663600
Location (UCSC)	Chr 12: 53.01 – 53.04 Mb	Chr 15: 102.07 – 102.1 Mb
PubMed search

1WI8, 2J76

1975

75705

ENSG00000063046

ENSMUSG00000058655

P23588

Q8BGD9

NM_001300821
NM_001417
NM_018507
NM_001330654

NM_145625

NP_001287750
NP_001317583
NP_001408

NP_663600.2
NP_663600

Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene.

EIF4B has been shown to interact and stimulate the activity of EIF4A and binds the eIF3 complex through the eIF3A subunit.

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Wikipedia