EFNB1

EFNB1
Identifiers
Aliases	EFNB1, CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2, ephrin B1
External IDs	MGI: 102708 HomoloGene: 3263 GeneCards: EFNB1
Gene ontology Molecular function • protein binding • ephrin receptor binding Cellular component • integral component of membrane • nucleus • extracellular exosome • membrane • membrane raft • integral component of plasma membrane • synapse • cytoplasm • plasma membrane Biological process • positive regulation of T cell proliferation • nervous system development • cell-cell signaling • T cell costimulation • multicellular organism development • neural crest cell migration • cell differentiation • cell adhesion • embryonic pattern specification • axon guidance • ephrin receptor signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1947	13641
Ensembl	ENSG00000090776	ENSMUSG00000031217
UniProt	P98172	P52795
RefSeq (mRNA)	NM_004429	NM_010110
RefSeq (protein)	NP_004420	NP_034240
Location (UCSC)	Chr X: 68.83 – 68.84 Mb	Chr X: 99.14 – 99.15 Mb
PubMed search

1947

13641

ENSG00000090776

ENSMUSG00000031217

P98172

P52795

NM_004429

NM_010110

NP_004420

NP_034240

Ephrin-B1 is a protein that in humans is encoded by the EFNB1 gene.

This gene encodes a member of the ephrin family. The encoded protein is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system.

Mutations in this protein are responsible for most cases of craniofrontonasal syndrome.

EFNB1 has been shown to interact with SDCBP.

...
Wikipedia