ECT2

ECT2

Protein ECT2 PDB 2cou.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3L46, 4N40

Identifiers

ECT2, ARHGEF31, epithelial cell transforming 2

External IDs

MGI: 95281 HomoloGene: 7298 GeneCards: ECT2

Gene location (Human)

Chr.	Chromosome 3 (human)

Band	No data available	Start	172,750,682 bp
Band	No data available	End	172,821,474 bp

Gene location (Mouse)

Chr.	Chromosome 3 (mouse)

Band	No data available	Start	27,097,222 bp
Band	No data available	End	27,153,878 bp

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• protein homodimerization activity • GTPase activator activity • signal transducer activity • protein binding • Rho GTPase binding • Rho guanyl-nucleotide exchange factor activity • guanyl-nucleotide exchange factor activity
Cellular component	• cytoplasm • centralspindlin complex • cell-cell junction • bicellular tight junction • spindle • cell junction • midbody • cleavage furrow • mitotic spindle • cytoskeleton • nucleus • cytosol
Biological process	• cellular response to calcium ion • cell differentiation • intracellular signal transduction • activation of GTPase activity • cytokinesis • nervous system development • cell division • positive regulation of cytokinesis • positive regulation of GTPase activity • positive regulation of neuron differentiation • bicellular tight junction assembly • cell morphogenesis • positive regulation of apoptotic process • cellular response to ionizing radiation • protein transport • positive regulation of I-kappaB kinase/NF-kappaB signaling • positive regulation of protein import into nucleus • cell cycle • regulation of protein kinase activity • regulation of Rho protein signal transduction • regulation of attachment of spindle microtubules to kinetochore • regulation of small GTPase mediated signal transduction • protein homooligomerization • activation of protein kinase activity • cellular response to hydrogen peroxide • transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


1894


13605


ENSG00000114346


ENSMUSG00000027699


Q9H8V3


Q07139

RefSeq (mRNA)


NM_001258315 NM_001258316 NM_018098


NM_001177625 NM_001177626 NM_007900

RefSeq (protein)

NP_001245244 NP_001245245 NP_060568 NP_001336023 NP_001336024
NP_001336025 NP_001336026 NP_001336027 NP_001336028 NP_001336029 NP_001336030 NP_001336031 NP_001336032 NP_001336033


NP_001171096 NP_001171097 NP_031926

Location (UCSC)

Chr 3: 172.75 – 172.82 Mb

Chr 3: 27.1 – 27.15 Mb

PubMed search

ENSG00000114346

ENSMUSG00000027699

NM_001258315
NM_001258316
NM_018098

NM_001177625
NM_001177626
NM_007900

NP_001336025
NP_001336026
NP_001336027
NP_001336028
NP_001336029
NP_001336030
NP_001336031
NP_001336032
NP_001336033

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Wikipedia

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