EAAT1

SLC1A3
Identifiers
Aliases	SLC1A3, EA6, EAAT1, GLAST, GLAST1, solute carrier family 1 member 3
External IDs	OMIM: 600111 MGI: 99917 HomoloGene: 20882 GeneCards: SLC1A3
Gene ontology Molecular function • amino acid binding • symporter activity • glutamate binding • L-glutamate transmembrane transporter activity • high-affinity glutamate transmembrane transporter activity • amino acid transmembrane transporter activity Cellular component • integral component of membrane • cell projection • membrane • plasma membrane • cell surface • neuronal cell body • neuron projection • cell periphery Biological process • chemical synaptic transmission • gamma-aminobutyric acid biosynthetic process • glutamate biosynthetic process • neuromuscular process controlling balance • response to light stimulus • cell morphogenesis involved in neuron differentiation • cranial nerve development • response to antibiotic • D-aspartate import • ion transport • sensory perception of sound • glutamate secretion • auditory behavior • neurotransmitter uptake • response to wounding • positive regulation of synaptic transmission • transport • glutamate metabolic process • response to drug • L-glutamate import • L-glutamate transport • amino acid transmembrane transport • L-glutamate transmembrane transport • transmembrane transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6507	20512
Ensembl	ENSG00000079215	ENSMUSG00000005360
UniProt	P43003	P56564
RefSeq (mRNA)	NM_001166695 NM_001166696 NM_001289939 NM_001289940 NM_004172	NM_148938
RefSeq (protein)	NP_001160167 NP_001160168 NP_001276868 NP_001276869 NP_004163	NP_683740.1 NP_683740
Location (UCSC)	Chr 5: 36.61 – 36.69 Mb	Chr 15: 8.63 – 8.71 Mb
PubMed search

6507

20512

ENSG00000079215

ENSMUSG00000005360

P43003

P56564

NM_001166695
NM_001166696
NM_001289939
NM_001289940
NM_004172

NM_148938

NP_001160167
NP_001160168
NP_001276868
NP_001276869
NP_004163

NP_683740.1
NP_683740

Solute carrier family 1 (glial high-affinity glutamate transporter), member 3, also known as SLC1A3, is a protein that, in humans, is encoded by the SLC1A3 gene. SLC1A3 is also often called the GLutamate ASpartate Transporter (GLAST) or Excitatory Amino Acid Transporter 1 (EAAT1) .

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