Dystrophin

DMD

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1DXX, 1EG3, 1EG4, 3UUN

Identifiers

Aliases

DMD, BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85, dystrophin

External IDs

OMIM: 300377 MGI: 94909 HomoloGene: 20856 GeneCards: DMD

Gene ontology
Molecular function	• nitric-oxide synthase binding • dystroglycan binding • vinculin binding • myosin binding • zinc ion binding • metal ion binding • structural constituent of cytoskeleton • protein binding • actin binding • structural constituent of muscle
Cellular component	• cytoplasm • cytosol • postsynaptic membrane • lateral plasma membrane • membrane • filopodium • cell-substrate junction • plasma membrane • synapse • dystrophin-associated glycoprotein complex • protein complex • cell surface • cell junction • Z disc • actin cytoskeleton • membrane raft • sarcolemma • costamere • syntrophin complex • neuron projection terminus • cytoskeleton • nucleus • filopodium membrane
Biological process	• response to muscle stretch • muscle attachment • regulation of ryanodine-sensitive calcium-release channel activity • cardiac muscle cell action potential • regulation of voltage-gated calcium channel activity • cardiac muscle contraction • muscle cell cellular homeostasis • negative regulation of peptidyl-cysteine S-nitrosylation • regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion • peptide biosynthetic process • muscle organ development • cellular protein complex assembly • regulation of heart rate • cellular protein localization • muscle fiber development • positive regulation of neuron differentiation • negative regulation of peptidyl-serine phosphorylation • positive regulation of neuron projection development • muscle filament sliding • positive regulation of sodium ion transmembrane transporter activity • regulation of cellular response to growth factor stimulus • regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum • motile cilium assembly • regulation of skeletal muscle contraction • regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion • cytoskeleton organization
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


1756


13405

Ensembl


ENSG00000198947


ENSMUSG00000045103

UniProt


P11532


P11531

RefSeq (mRNA)

NM_000109 NM_004006 NM_004007 NM_004009 NM_004010
NM_004011 NM_004012 NM_004013 NM_004014 NM_004015 NM_004016 NM_004017 NM_004018 NM_004019 NM_004020 NM_004021 NM_004022 NM_004023

NM_007868 NM_001314034 NM_001314035 NM_001314036 NM_001314037
NM_001314038

RefSeq (protein)

NP_000100 NP_003997 NP_004000 NP_004001 NP_004002
NP_004003 NP_004004 NP_004005 NP_004006 NP_004007 NP_004008 NP_004009 NP_004010 NP_004011 NP_004012 NP_004013 NP_004014

NP_031894.1 NP_001300963 NP_001300964 NP_001300965 NP_001300966
NP_001300967 NP_031894

Location (UCSC)

Chr X: 31.1 – 33.34 Mb

Chr X: 82.95 – 85.21 Mb

PubMed search

1DXX, 1EG3, 1EG4, 3UUN

NM_004011
NM_004012
NM_004013
NM_004014
NM_004015
NM_004016
NM_004017
NM_004018
NM_004019
NM_004020
NM_004021
NM_004022
NM_004023

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