Dystroglycan

DAG1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1EG4, 2MK7

Identifiers

Aliases

DAG1, 156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9, MDDGA9, dystroglycan 1

External IDs

OMIM: 128239 MGI: 101864 HomoloGene: 3234 GeneCards: DAG1

Gene ontology
Molecular function	• calcium ion binding • protein binding • virus receptor activity • alpha-actinin binding • vinculin binding • actin binding • tubulin binding • structural constituent of muscle • SH2 domain binding • laminin binding • laminin-1 binding • dystroglycan binding
Cellular component	• cell-cell junction • cell-cell adherens junction • nucleus • synapse • extracellular region • contractile ring • filopodium • node of Ranvier • costamere • lamellipodium • dystroglycan complex • membrane raft • cell junction • cytoskeleton • membrane • extracellular exosome • basolateral plasma membrane • postsynaptic membrane • sarcolemma • cytoplasm • integral component of membrane • focal adhesion • plasma membrane • dystrophin-associated glycoprotein complex • nucleoplasm • basement membrane • cytosol • extracellular space • endoplasmic reticulum lumen • Golgi lumen • plasma membrane raft • external side of plasma membrane
Biological process	• NLS-bearing protein import into nucleus • extracellular matrix organization • viral process • regulation of embryonic cell shape • response to peptide hormone • regulation of epithelial to mesenchymal transition • positive regulation of basement membrane assembly involved in embryonic body morphogenesis • viral entry into host cell • regulation of gastrulation • cytoskeletal anchoring at plasma membrane • negative regulation of cell migration • Schwann cell development • membrane protein ectodomain proteolysis • calcium-dependent cell-matrix adhesion • negative regulation of MAPK cascade • nerve maturation • microtubule anchoring • commissural neuron axon guidance • branching involved in salivary gland morphogenesis • negative regulation of protein kinase B signaling • morphogenesis of an epithelial sheet • myelination in peripheral nervous system • basement membrane organization • epithelial tube branching involved in lung morphogenesis • modulation by virus of host morphology or physiology • protein O-linked glycosylation • positive regulation of cell-matrix adhesion • aging • Schwann cell differentiation • response to denervation involved in regulation of muscle adaptation • nerve development • axon regeneration • positive regulation of myelination • skeletal muscle tissue regeneration • positive regulation of protein kinase activity • positive regulation of oligodendrocyte differentiation • cellular response to mechanical stimulus • cellular response to cholesterol
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


1605


13138

Ensembl


ENSG00000173402


ENSMUSG00000039952

UniProt


Q14118


Q62165

RefSeq (mRNA)

NM_004393 NM_001165928 NM_001177634 NM_001177635 NM_001177636
NM_001177637 NM_001177638 NM_001177639 NM_001177640 NM_001177641 NM_001177642 NM_001177643 NM_001177644

NM_001276481 NM_001276482 NM_001276485 NM_001276486 NM_001276492
NM_001276493 NM_001276494 NM_010017

RefSeq (protein)

NP_001159400 NP_001171105 NP_001171106 NP_001171107 NP_001171108
NP_001171109 NP_001171110 NP_001171111 NP_001171112 NP_001171113 NP_001171114 NP_001171115 NP_004384

NP_001263410.1 NP_001263411.1 NP_001263414.1 NP_001263415.1 NP_001263421.1
NP_001263422.1 NP_034147.1 NP_001263410 NP_001263411 NP_001263414 NP_001263415 NP_001263421 NP_001263422 NP_034147

Location (UCSC)

Chr 3: 49.47 – 49.54 Mb

Chr 9: 108.2 – 108.26 Mb

PubMed search

NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177643
NM_001177644

NM_001276493
NM_001276494
NM_010017

NP_001171109
NP_001171110
NP_001171111
NP_001171112
NP_001171113
NP_001171114
NP_001171115
NP_004384

...
Wikipedia