Duke of Clarence and St Andrews was a title awarded to a prince of the British Royal family. The creation was in the Peerage of Great Britain.
While there had been several creations of Dukes of Clarence (and there was later a Duke of Clarence and Avondale), the only creation of a Duke of Clarence and St Andrews was in 1789 for The Prince William, third son of King George III. When William succeeded his brother to the throne in 1830, the dukedom merged in the crown.