"Duffle Bag Boy" is a song by American hip hop duo Playaz Circle, released as the debut lead single from their debut album, Supply & Demand (2007). The song features a guest appearance from fellow American rapper Lil Wayne and was produced by M16 and Liam Kantwill. The song peaked in the Top 40 of the U.S. Billboard Hot 100, reaching number 15.

The music video directed by Disturbing Tha Peace CEO Chaka Zulu begins with Tity Boi getting up from bed for breakfast. He gets dressed and rides in a Lamborghini Gallardo, in which he picks up Lil Wayne, handing him a duffle bag. They then head to a concert. Meanwhile, Dolla Boy sells some CDs to a boy in exchange for a duffle bag, then receives a text message to meet Tity Boi and Lil Wayne. At the end of the video, all three of them are seen performing together.

The official remix features Birdman, Juelz Santana and a new verse from Lil Wayne (who only sang the song's chorus in the original version). At the 2007 BET Hip Hop Awards, Playaz Circle and Lil Wayne performed the song with a new guest verse from fellow American rapper and DTP label-boss Ludacris.

Miami-based rapper Lil' Brianna, released a freestyle over the song's instrumental for her 2007 mixtape, Princess of Miami. UK rapper Kano, released a freestyle over the song's instrumental for his MC No.1 mixtape. Other remixes include a Travis Barker remix and a Sean P remix, respectively. American rappers Rick Ross and Young Jeezy also have their own respective remixes.

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