Dr. Mario 64

Dr. Mario 64
North American box art
Developer(s)	Nintendo IRD
Publisher(s)	Nintendo
Director(s)	Hitoshi Yamagami Yoshiyuki Kato
Producer(s)	Genyo Takeda Junichi Yakahi
Designer(s)	Hitoshi Yamagami Kazushi Maeda Yohei Fujigawa
Composer(s)	Seiichi Tokunaga
Series	Dr. Mario
Platform(s)	Nintendo 64, iQue Player
Release	Nintendo 64 NA: April 8, 2001 iQue Player CHN: November 17, 2003
Genre(s)	Puzzle
Mode(s)	Single-player, multiplayer

Dr. Mario 64 is a Mario tile-matching action puzzle video game developed and published by Nintendo for the Nintendo 64. The game was released in North America on April 8, 2001 and the final Mario and Wario game to be released on the Nintendo 64. The game is an enhanced remake of Dr. Mario, which was originally released for the Nintendo Entertainment System and Game Boy consoles in 1990. The game's soundtrack was composed by Seiichi Tokunaga, featuring arrangements of classic Dr. Mario tunes and new compositions.

It was re-released along with Panel de Pon and Yoshi's Cookie in a GameCube video game called Nintendo Puzzle Collection in 2003, which was only released in Japan.

Like its predecessor, Dr. Mario 64 is a falling block tile-matching video game. The playing field is represented on-screen as a medicine bottle populated with viruses of three colors: red, blue, and yellow. The main objective of the game to clear the playing field of all the viruses using two-colored medical capsules dropped into the bottle. The player manipulates the capsules as they fall, moving them left or right and rotating such that they are positioned alongside the viruses and any existing capsules. When four or more capsule halves or viruses of the same colour are aligned in horizontal or vertical configurations, they are removed from play. The player receives a game over if the playing field fills up with capsules such that they obstruct the bottle's narrow neck. Points are awarded when viruses are destroyed.