The Dorena-Hickman Ferry is a ferry across the Mississippi River between Dorena, Missouri and Hickman, Kentucky. A single boat takes vehicular traffic across the river seven days a week during daylight hours.
It provides the only direct road connection between the two U.S. states' mainlands; however, they are indirectly connected at Cairo, Illinois via U.S. 60 & U.S. 62 over the Cairo Mississippi River Bridge and the Cairo Ohio River Bridge, both just above the mouth of the Ohio River. Nonetheless, since the Ohio is the historic division between the upper & lower parts of the Mississippi, this ferry is the farthest-upstream crossing of the Lower Mississippi; the two Cairo bridges are the farthest-downstream crossings of the Upper Mississippi & the Ohio, respectively.