Domhnall Mac Murchada (died 20 November 763), called Domnall Midi (Donald of Meath), was High King of Ireland. He belonged to the Clann Cholmáin branch of the Uí Néill. Clann Cholmáin's pre-eminence among the southern Uí Néill, which would last until the rise of Brian Bóruma and the end of the Uí Néill dominance in Ireland, dates from his lifetime.
Domnall was chief of Clann Cholmáin for almost fifty years, and High King of Ireland for twenty. In spite of this, and his importance as a dynast, the Irish annals contain relatively few reports of his activities. He was a patron of the Columban churches, particularly Durrow Abbey, where he is buried.
Domnall was a son of Murchad mac Diarmato. He had at least one sibling, a brother named Coirpre who died in 749, and it is likely that the Bressal mac Murchado who was killed in 764 was also his brother. Domnall's father ruled as king of Uisnech from the death of his father, Diarmait Dian, in 689 until his own death in 715. He was killed by Conall Grant of the Síl nÁedo Sláine branch of the southern Uí Néill. A year earlier Murchad drove out Conall's nephew Fogartach mac Néill, probably the chief king among the southern Uí Néill, who was exiled to Britain. The notice of Murchad's death calls him "king of the Uí Néill", meaning that he was the southern deputy of then-High King Fergal mac Máele Dúin of the northern Cenél nEógain.
According to later king lists such as those in the Book of Leinster, Domnall succeeded his father as king of Uisnech on the latter's death. If this is correct, the Irish annals take no notice of him, and it is not until 730 that he is first mentioned. During this time, the internecine conflict within the Síl nÁedo Sláine continued. Fergal mac Máele Dúin had died in battle in Leinster in 722. Fogartach mac Néill, who had returned to Ireland in 716 and was once again chief king among the southern Uí Néill, later Fergal's deputy, succeeded him. Fogartach was killed in battle against his Síl nÁedo Sláine kinsman Cináed mac Írgalaig in 724. Cináed was killed in 728 fighting against Flaithbertach mac Loingsig of the northern Cenél Conaill who became High King after this victory.