Diminazene

Diminazene

Clinical data
Trade names	Azidin, Berenil, Ganasag, Pirocide
Routes of administration	IM, SC
ATCvet code	QP51AF01 (WHO) QP51AX07 (WHO)
Legal status
Legal status	Veterinary use only
Identifiers
IUPAC name 4-[2-(4-Carbamimidoylphenyl)iminohydrazinyl]benzenecarboximidamide
Synonyms	4,4'-(1-Triazene-1,3-diyl)bis(benzenecarboximidamide)
CAS Number	536-71-0 aceturate: 908-54-3
PubChem CID	2354
ChemSpider	2264
UNII	Y5G36EEA5Z aceturate: JI8SAD85NO
ChEBI	CHEBI:81724 Y
ChEMBL	CHEMBL124025 Y
ECHA InfoCard	100.007.860
Chemical and physical data
Formula	C14H15N7
Molar mass	281.316 g/mol
3D model (Jmol)	Interactive image
SMILES C1=CC(=CC=C1C(=N)N)N/N=N/C2=CC=C(C=C2)C(=N)N
InChI InChI=1S/C14H15N7/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18)(H,19,20) Key:XNYZHCFCZNMTFY-UHFFFAOYSA-N

Diminazene (INN; also known as diminazen) is an anti-infective medication for animals that is sold under a variety of brand names (see drugbox). It is effective against certain protozoa such as Babesia, Trypanosoma and Cytauxzoon. The drug may also be effective against certain bacteria including Brucella and .

Chemically it is a di-amidine, and it is used in form of the aceturate (N-acetylglycinate).

The mechanism is not well understood; it probably inhibits DNA replication, but also has affinity to RNA.

Acute side effects include vomiting, diarrhoea and hypotension (low blood pressure). Diminazen can harm the liver, kidneys and brain, which is potentially life-threatening; especially camels are susceptible to these effects.