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Dihydroorotase

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
4by3.jpg
Dihydroorotase (fragment) dimer, Human
Identifiers
Symbol CAD
Entrez 790
HUGO 1424
OMIM 114010
RefSeq NM_004341
UniProt P27708
Other data
EC number 3.5.2.3
Locus Chr. 2 p22-p21

Dihydroorotase (EC 3.5.2.3, carbamoylaspartic dehydrase, dihydroorotate hydrolase) is an enzyme which converts carbamoyl aspartic acid into 4,5-dihydroorotic acid in the biosynthesis of pyrimidines. It forms a multifunctional enzyme with carbamoyl phosphate synthetase and aspartate transcarboymalase.


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