Diethyl sulfate

Diethyl sulfate

Names
Other names Sulfuric acid diethyl ester
Identifiers
CAS Number	64-67-5 Y
3D model (Jmol)	Interactive image
ChemSpider	5931 Y
ECHA InfoCard	100.000.536
KEGG	C14706 Y
PubChem CID	6163
RTECS number	WS7875000
InChI InChI=1S/C4H10O4S/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3 Y Key: DENRZWYUOJLTMF-UHFFFAOYSA-N Y InChI=1/C4H10O4S/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3 Key: DENRZWYUOJLTMF-UHFFFAOYAR
SMILES O=S(=O)(OCC)OCC
Properties
Chemical formula	C4H10O4S
Molar mass	154.18 g·mol−1
Appearance	Colorless liquid
Density	1.2 g/mL
Melting point	−25 °C (−13 °F; 248 K)
Boiling point	209 °C (408 °F; 482 K) (decomposes)
Solubility in water	0.7 g/100 mL
Vapor pressure	0.29 mm Hg
Magnetic susceptibility (χ)	-86.8·10−6 cm3/mol
Hazards
EU classification (DSD) (outdated)	Toxic (T) Carc. Cat. 2 Muta. Cat. 2
R-phrases (outdated)	R45 R46 R20/21/22 R34
S-phrases (outdated)	S53 S45
NFPA 704	1 3 1
Flash point	104 °C (219 °F; 377 K)
Related compounds
Related compounds	Dimethyl sulfate; diethyl sulfite
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y  (what is YN ?)
Infobox references

Diethyl sulfate is a highly toxic and likely carcinogenic chemical compound with formula (C₂H₅)₂SO₄. It occurs as a colorless, oily liquid with a faint peppermint odor and is corrosive.

Diethyl sulfate is used as an alkylating agent to prepare ethyl derivatives of phenols, amines, and thiols. It is used to manufacture dyes and textiles.

Diethyl sulfate is a strong alkylating agent which ethylates DNA and thus is genotoxic. There is not sufficient evidence for the carcinogenic properties of diethyl sulfate in humans, but there is in animals. It is classified as a Group 2A carcinogen by the IARC

It can be prepared by absorbing ethylene into concentrated sulfuric acid or by fuming sulfuric acid into diethyl ether or ethanol.