Diego Pablo Seguí González [say-gee] (born August 17, 1937) is a Cuban former Major League Baseball pitcher. Listed at 6' 0" (1.83 m), 190 lb. (86 k), Seguí batted and threw right handed. He was born in Holguín, Cuba. His son, David Seguí, is a former major league first baseman.

A forkball specialist, Seguí pitched for the Kansas City Athletics, Washington Senators, Oakland Athletics, Seattle Pilots, St. Louis Cardinals, Boston Red Sox and Seattle Mariners in all or part of 16 seasons spanning 1962–1977.

In 1970 with Oakland, Seguí won 10 games as a reliever and starter, while leading the American League pitchers with a 2.56 ERA.

On June 7, 1972, he was sent by St. Louis along with Reggie Cleveland and Terry Hughes to the Red Sox, in the same trade that brought John Curtis, Lynn McGlothen and Mike Garman to the Cardinals.

Seguí holds the unique distinction of having pitched for both of Seattle's major league baseball teams, the Pilots and the Mariners, in the first game ever played by each franchise. In these contests, he earned a save for the Pilots in 1969, and absorbed the opening-day loss for the Mariners in 1977.

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