Dexatrim

Dexatrim is an over-the-counter (OTC) dietary supplement meant to assist with weight loss. Dexatrim claims it "gives you the power to lose weight, curb binges, and keep you in control of your diet." Current Dexatrim products available are in capsule form and include Dexatrim Max Complex 7, Dexatrim Max Daytime Appetite Control, Dexatrim Natural Green Tea, and Dexatrim Natural Extra Energy. The major active ingredients found in current Dexatrim products include caffeine, green tea extract, Asian (Panax) ginseng root extract, and dehydroepiandrosterone (DHEA).

The caffeine content in the daily recommended dose of Dexatrim products ranges from 50–400 mg per day. There are a number of studies showing that caffeine has a short-term stimulatory effect on basal metabolic rate. However, in 1992, in a double-blind placebo controlled study, caffeine (at a dose of 200 mg daily) was found to be no more effective in promoting weight loss as compared to a placebo. Potential side effects of caffeine may include insomnia, anxiety, gastrointestinal discomfort, diarrhea, headaches and abnormal heart beat.

Green tea extract is currently used for a variety of conditions including improving mental alertness and aiding in weight loss. There is currently insufficient data to determine the efficacy of green tea extract in aiding weight loss. In addition to the potential side effects from the caffeine content in green tea extract, there is some risk of liver problems associated with green tea extract consumption. Liver problems have not been observed with the use of green tea in beverages.

Asian (panax) ginseng is used for a wide variety of conditions—without US Food & Drug Administration (FDA) approval—including aiding in thinking and memory, diabetes, erectile dysfunction, premature ejaculation, and aiding in weight loss. Across a wide scope of studies, scientific data does not support the health claims associated with using ginseng. Short-term use of ginseng (under 3 months) is unlikely to produce side effects and appears safe for most people. Side effects, often associated with longer term use, can include headaches, insomnia, and gastrointestinal problems. There are many conditions in which ginseng use has special precautions and warnings. These include pregnancy, diabetes, auto-immune diseases, and bleeding disorders.

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